Endocrine Abstracts

Late-onset hypogonadism (LOH) remains a debatable entity in terms of diagnosis and management. However, the finding of primary hypogonadism (PHG) in ageing men, in the absence of organic cause, provides an unequivocal biochemical diagnosis. Indeed, it has been established in European Male Ageing Study (EMAS) that PHG, and not secondary hypogonadism, is strongly associated with advanced age and multi-comorbidities. That would be consistent with the underlying pathophysiology of...